ESSAY ON: Nitric Oxide Synthase

Number of Pages 15

This research paper: 15 pages in length. Nitric oxide (NO), a toxic, colorless gas that is formed by oxidation of nitrogen or ammonia, has long been considered a threat to man's physical being; however, current research has uncovered some startling evidence that nitric oxide is not only innocuous to the human body, but findings have indicated that it actually helps address certain illnesses and diseases. As an inorganic gas, it is a responsible component of regulated bodily blood flow and arterial pressure; without nitric oxide, blood circulation would not move through the body with necessary regularity. Associated with nitric oxide is endothelium derived relaxing factor (EDRF), for which nitric oxide provides the biological properties. Nitric oxide has other important physiological duties, inasmuch as it is considered a messenger molecule in the central and periferic nervous system and a mediator of immune and inflammatory responses. Nitric oxide synthase (NOS) is a required component in the formation of nitric oxide as it exists from a basis of L-arginine amino acid. Humans have been found to house three nitric oxide synthase isoenzymes, including isoform I, expressed constitutively in brain, isoform II usually not constitutively expressed but can be present in cytokine-induced cells; and isoform III expressed in endothelials cells. The writer discusses the various associations in relation to nitric oxide synthase and the human body. Bibliography lists 17 sources.


File: LM1_TLCnitrc.wps


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